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gst  (Carna Inc)


Bioz Verified Symbol Carna Inc is a verified supplier
Bioz Manufacturer Symbol Carna Inc manufactures this product  
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  • 96

    Structured Review

    Carna Inc gst
    Gst, supplied by Carna Inc, used in various techniques. Bioz Stars score: 96/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/01-127/PKACa/us11248004-1036-38-39
    Average 96 stars, based on 4 article reviews
    gst - by Bioz Stars, 2026-09
    96/100 stars

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    Related Articles

    Control:

    Article Title: Substituted isoquinolines as rock kinase inhibitors
    Article Snippet: Dose-response curves for compounds of the present invention were determined using a fluorescence coupling enzymatic assay using purified C-terminal truncated human ROCK1 catalytic domain (amino acids 1-477 of accession number NP_005397.1) fused to GST (Carna BioSciences, Catalog #01-109) and purified C-terminal truncated human ROCK2 enzyme kinase domain (amino acids 1-553 of accession number NP_004841.2) fused to GST (Carna BioSciences, Catalog #01-110). .. In addition, full length cGMP-dependent protein kinase 1 (PKG or PRKG1; amino acids 1-686 of accession number NP_006249.1) fused to GST (Carna BioSciences, Catalog #01-142), full length PKACa (PRKACA; amino acids 1-351 of accession number NP_002721.1) fused to GST (Carna BioSciences, Catalog #01-127), and C-terminal truncated human AKT1 catalytic domain (amino acids 104-480 of accession number NP_005154.1) fused to GST (Carna Biosciences, Catalog #01-101) were used as a control to measure any non-desired off-target kinase activity. ..

    Activity Assay:

    Article Title: Substituted isoquinolines as rock kinase inhibitors
    Article Snippet: Dose-response curves for compounds of the present invention were determined using a fluorescence coupling enzymatic assay using purified C-terminal truncated human ROCK1 catalytic domain (amino acids 1-477 of accession number NP_005397.1) fused to GST (Carna BioSciences, Catalog #01-109) and purified C-terminal truncated human ROCK2 enzyme kinase domain (amino acids 1-553 of accession number NP_004841.2) fused to GST (Carna BioSciences, Catalog #01-110). .. In addition, full length cGMP-dependent protein kinase 1 (PKG or PRKG1; amino acids 1-686 of accession number NP_006249.1) fused to GST (Carna BioSciences, Catalog #01-142), full length PKACa (PRKACA; amino acids 1-351 of accession number NP_002721.1) fused to GST (Carna BioSciences, Catalog #01-127), and C-terminal truncated human AKT1 catalytic domain (amino acids 104-480 of accession number NP_005154.1) fused to GST (Carna Biosciences, Catalog #01-101) were used as a control to measure any non-desired off-target kinase activity. ..

    Recombinant:

    Article Title: TDP 2 negatively regulates axon regeneration by inducing SUMO ylation of an Ets transcription factor
    Article Snippet: .. Kinase reactions were performed in a final volume of 20 μl buffer consisting of 25 mM MOPS (pH 7.2), 12.5 mM glycerol phosphate, 25 mM MgCl 2 , 2 mM EDTA, 0.25 mM DTT, 200 μM ATP, and 0.4 μg of recombinant PKA (Carna Biosciences). ..

    other:

    Article Title: UNC5293, a potent, orally available and highly MERTK-selective inhibitor.
    Article Snippet: Inhibition of MER receptor tyrosine kinase (MERTK) causes direct tumor cell killing and stimulation of the innate immune response.. Therefore, MERTK has been identified as a therapeutic target in a wide variety of human tumors.. Clinical trials targeting MERTK have recently been initiated, however, none of these drugs are MERTK-specific.



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