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trichloroacetic acid  (Chem Impex International)


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    Chem Impex International trichloroacetic acid
    Trichloroacetic Acid, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/00820/Trichloroacetic+acid/10__36721_slash_pjps__2025__38__2__reg__12747__1-63-9-23
    Average 95 stars, based on 2 article reviews
    trichloroacetic acid - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Modification:

    Article Title: The protective role of Calotropis procera Linn against cisplatin-induced oxidative stress, insight into antioxidant effects
    Article Snippet: Potassium dihydrogen phosphate anhydrous (BMP-132-X1) was obtained from BIO-M. Trichloroacetic acid (2515) was obtained from SMART-LAB. Nitrobenzoic acid (00169- 2019050901) was obtained from CHEM-IMPEX INT.

    Transfection:

    Article Title: The protective role of Calotropis procera Linn against cisplatin-induced oxidative stress, insight into antioxidant effects
    Article Snippet: Potassium dihydrogen phosphate anhydrous (BMP-132-X1) was obtained from BIO-M. Trichloroacetic acid (2515) was obtained from SMART-LAB. Nitrobenzoic acid (00169- 2019050901) was obtained from CHEM-IMPEX INT.

    Concentration Assay:

    Article Title: The protective role of Calotropis procera Linn against cisplatin-induced oxidative stress, insight into antioxidant effects
    Article Snippet: Potassium dihydrogen phosphate anhydrous (BMP-132-X1) was obtained from BIO-M. Trichloroacetic acid (2515) was obtained from SMART-LAB. Nitrobenzoic acid (00169- 2019050901) was obtained from CHEM-IMPEX INT.

    Inhibition:

    Article Title: The protective role of Calotropis procera Linn against cisplatin-induced oxidative stress, insight into antioxidant effects
    Article Snippet: Potassium dihydrogen phosphate anhydrous (BMP-132-X1) was obtained from BIO-M. Trichloroacetic acid (2515) was obtained from SMART-LAB. Nitrobenzoic acid (00169- 2019050901) was obtained from CHEM-IMPEX INT.



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    tca  (Chem Impex International)
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    Time-dependent uptake of taurochenodeoxycholate (TCDCA; 5 µM), glycochenodeoxycholate (GCDCA; 5 µM), taurocholate <t>(TCA;</t> 5 µM), and <t>glycocholate</t> <t>(GCA;</t> 5 µM). Transport studies were performed using 5.0 × 105 viable cells/well in modified extracellular fluid buffer, as described previously (Malinen et al., 2018, 2019). Solid and open symbols represent OSTab- and Mock-mediated bile acid uptake, respectively. Data are presented as mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown for clarity. Uptake data points from Mock cells that are not visible are hidden behind the TCDCA data corresponding to Mock cells. Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.
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    Image Search Results


    Time-dependent uptake of taurochenodeoxycholate (TCDCA; 5 µM), glycochenodeoxycholate (GCDCA; 5 µM), taurocholate (TCA; 5 µM), and glycocholate (GCA; 5 µM). Transport studies were performed using 5.0 × 105 viable cells/well in modified extracellular fluid buffer, as described previously (Malinen et al., 2018, 2019). Solid and open symbols represent OSTab- and Mock-mediated bile acid uptake, respectively. Data are presented as mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown for clarity. Uptake data points from Mock cells that are not visible are hidden behind the TCDCA data corresponding to Mock cells. Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.

    Journal: Toxicological Sciences

    Article Title: Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

    doi: 10.1093/toxsci/kfaa052

    Figure Lengend Snippet: Time-dependent uptake of taurochenodeoxycholate (TCDCA; 5 µM), glycochenodeoxycholate (GCDCA; 5 µM), taurocholate (TCA; 5 µM), and glycocholate (GCA; 5 µM). Transport studies were performed using 5.0 × 105 viable cells/well in modified extracellular fluid buffer, as described previously (Malinen et al., 2018, 2019). Solid and open symbols represent OSTab- and Mock-mediated bile acid uptake, respectively. Data are presented as mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown for clarity. Uptake data points from Mock cells that are not visible are hidden behind the TCDCA data corresponding to Mock cells. Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.

    Article Snippet: GCA, TCA (Chem-Impex International, Wood Dale, Illinois), GCDCA and TCDCA were used as unlabeled, putative substrates for bile acid transport studies.

    Techniques: Modification, Transfection

    Concentration-dependent uptake rate (at substrate concentrations of 5–500 µM) of taurochenodeoxycholate (TCDCA), glycochenodeoxycholate (GCDCA), taurocholate (TCA), and glycocholate (GCA) by OSTα/β. Solid symbols represent the rate of bile acid uptake (30 s) after subtracting uptake in Mock cells from uptake in OSTab cells. Data are presented as mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown for clarity. Linear regression using GraphPad Prism version 8.2.0 was used to derive the slope ± SD approximating OSTα/β-mediated uptake clearance [CLuptake = Vmax/(Km+C)] of conjugated bile acid species. Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.

    Journal: Toxicological Sciences

    Article Title: Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

    doi: 10.1093/toxsci/kfaa052

    Figure Lengend Snippet: Concentration-dependent uptake rate (at substrate concentrations of 5–500 µM) of taurochenodeoxycholate (TCDCA), glycochenodeoxycholate (GCDCA), taurocholate (TCA), and glycocholate (GCA) by OSTα/β. Solid symbols represent the rate of bile acid uptake (30 s) after subtracting uptake in Mock cells from uptake in OSTab cells. Data are presented as mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown for clarity. Linear regression using GraphPad Prism version 8.2.0 was used to derive the slope ± SD approximating OSTα/β-mediated uptake clearance [CLuptake = Vmax/(Km+C)] of conjugated bile acid species. Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.

    Article Snippet: GCA, TCA (Chem-Impex International, Wood Dale, Illinois), GCDCA and TCDCA were used as unlabeled, putative substrates for bile acid transport studies.

    Techniques: Concentration Assay, Transfection

    Inhibition of OSTα/β-mediated uptake of taurochenodeoxycholate (TCDCA; 5 µM), glycochenodeoxycholate (GCDCA; 5 µM), taurocholate (TCA; 5 µM), and glycocholate (GCA; 5 µM) by fidaxomicin, troglitazone sulfate, and ethinyl estradiol over a concentration range of 0.125–200 µM. Solid symbols represent bile acid uptake after subtracting uptake in Mock cells from uptake in OSTab cells, followed by vehicle control normalization. Data represent mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown. The apparent half-maximal inhibitory concentration and corresponding 95% confidence interval for each bile acid substrate were determined by nonlinear regression using GraphPad Prism version 8.2.0 (Table 2). Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.

    Journal: Toxicological Sciences

    Article Title: Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

    doi: 10.1093/toxsci/kfaa052

    Figure Lengend Snippet: Inhibition of OSTα/β-mediated uptake of taurochenodeoxycholate (TCDCA; 5 µM), glycochenodeoxycholate (GCDCA; 5 µM), taurocholate (TCA; 5 µM), and glycocholate (GCA; 5 µM) by fidaxomicin, troglitazone sulfate, and ethinyl estradiol over a concentration range of 0.125–200 µM. Solid symbols represent bile acid uptake after subtracting uptake in Mock cells from uptake in OSTab cells, followed by vehicle control normalization. Data represent mean ± SD (n = 3, in triplicate), as described in the Materials and Methods section. Only the SD in the upper direction is shown. The apparent half-maximal inhibitory concentration and corresponding 95% confidence interval for each bile acid substrate were determined by nonlinear regression using GraphPad Prism version 8.2.0 (Table 2). Abbreviations: Mock cells, mock-transfected cells; OSTab cells, OSTα/β-overexpressing cells.

    Article Snippet: GCA, TCA (Chem-Impex International, Wood Dale, Illinois), GCDCA and TCDCA were used as unlabeled, putative substrates for bile acid transport studies.

    Techniques: Inhibition, Concentration Assay, Transfection