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sodium taurocholate  (Chem Impex International)


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    Chem Impex International sodium taurocholate
    Sodium Taurocholate, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/00511/Taurocholic+acid+sodium+salt+hydrate/pm37027059-109-8-12
    Average 95 stars, based on 12 article reviews
    sodium taurocholate - by Bioz Stars, 2026-09
    95/100 stars

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    Activity Assay:

    Article Title: Metataxonomic analysis of microbiota from Pakistani dromedary camelids milk and characterization of a newly isolated Lactobacillus fermentum strain with probiotic and bio-yogurt starter traits.
    Article Snippet: This study was undertaken to investigate the starter and probiotic potential of lactic acid bacteria isolated from dromedarian camel’s milk using both culture-dependent and -independent approaches and metataxonomic analysis.. Strains of lactic acid bacteria recovered were examined in vitro for tolerance to gastric acidity, bile, and lysozyme.. Bile salt hydrolysis, serum cholesterol-lowering, oxalate degradation, proteolytic activity, exopolysaccharide production, and cell surface characteristics necessary for colonizing intestinal mucosa were also evaluated.

    Article Title: Aggrandizement of fermented cucumber through the action of autochthonous probiotic cum starter strains of Lactiplantibacillus plantarum and Pediococcus pentosaceus
    Article Snippet: .. For evaluating BSH activity, LAB strains were tested using a plate assay method (Ji et al. ) on MRS agar medium supplemented with 0.37 g/L CaCl 2 (Daejung, Korea) and 0.5% (w/v) different bile salts: sodium tauroglycocholate TGC, sodium taurodeoxycholate TDC (Himedia, India), sodium taurocholate TC (Chem-Impex International, Inc., USA), and sodium deoxycholate DC (Sigma-Aldrich, USA). .. The capacity to assimilate cholesterol was tested in MRS broth using 100 μg/mL water-soluble PEG-Cholesterol (Sigma Aldrich, USA) (Tomaro-Duchesneau et al. ).

    Incubation:

    Article Title: Metataxonomic analysis of microbiota from Pakistani dromedary camelids milk and characterization of a newly isolated Lactobacillus fermentum strain with probiotic and bio-yogurt starter traits.
    Article Snippet: This study was undertaken to investigate the starter and probiotic potential of lactic acid bacteria isolated from dromedarian camel’s milk using both culture-dependent and -independent approaches and metataxonomic analysis.. Strains of lactic acid bacteria recovered were examined in vitro for tolerance to gastric acidity, bile, and lysozyme.. Bile salt hydrolysis, serum cholesterol-lowering, oxalate degradation, proteolytic activity, exopolysaccharide production, and cell surface characteristics necessary for colonizing intestinal mucosa were also evaluated.

    Polymerase Chain Reaction:

    Article Title: Metataxonomic analysis of microbiota from Pakistani dromedary camelids milk and characterization of a newly isolated Lactobacillus fermentum strain with probiotic and bio-yogurt starter traits.
    Article Snippet: This study was undertaken to investigate the starter and probiotic potential of lactic acid bacteria isolated from dromedarian camel’s milk using both culture-dependent and -independent approaches and metataxonomic analysis.. Strains of lactic acid bacteria recovered were examined in vitro for tolerance to gastric acidity, bile, and lysozyme.. Bile salt hydrolysis, serum cholesterol-lowering, oxalate degradation, proteolytic activity, exopolysaccharide production, and cell surface characteristics necessary for colonizing intestinal mucosa were also evaluated.

    Saline:

    Article Title: Auranofin, at clinically achievable dose, protects mice and prevents recurrence from Clostridioides difficile infection.
    Article Snippet: Yeast extract, sucrose and L-cysteine were purchased from Fisher Scientific (Fail Lawn, NJ, USA). .. Phosphate buffered saline (PBS) (Corning, Manassas, VA, USA), pepsin from porcine gastric mucosa, pancreatin from porcine pancreas, hydrochloric acid (HCl), sodium chloride (NaCl), sodium hydroxide (NaOH), bovine serum albumin (Sigma-Aldrich, Saint Louis, MO, USA), monobasic potassium phosphate (KH2PO4) (Macron chemicals, Center Valley, PA, USA), vancomycin hydrochloride, gentamicin sulfate, kanamycin monosulfate, taurocholic acid (Chem-Impex, Wood Dale, IL, USA), metronidazole (Alfa Aesar, Ward Hill, MA, USA), and colistin sulfate, fidaxomicin (Cayman Chemical, Ann Arbor, MI, USA) were purchased commercially. ..

    other:

    Article Title: Non-invasive caffeinated-nanovesicles as adipocytes-targeted therapy for cellulite and localized fats
    Article Snippet: Sodium taurocholate (STC) was supplied by Chem-Impex International, Inc. (USA).

    Article Title: Novel dermal nanobilosomes with promising browning effect of adipose tissue for management of obesity
    Article Snippet: Obesity is a medical problem that increases the risk of various diseases.. Besides, obese people sometimes feel discrimination which results in social isolation and severe depression.. Therefore, the management of obesity and localized fats gains a great interest.

    Virus:

    Article Title: Bile acids regulate lipid metabolism through selective actions on fatty acid absorption.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit polyclonal anti-CYP7A1 Novus Cat#NBP3-04836 lot 5500012145; RRID: AB_2255011 Rabbit polyclonal anti-CYP8B1 Abcam Cat#ab191910; RRID: AB_2828000 Rabbit polyclonal anti- rat CYP2C22 (mouse CYP2C70) Gift from Edward T. Morgan (Emory University) N/A Rabbit monoclonal anti-PDI Cell Signaling Technology Cat#3501S; RRID: AB_2156433 Rabbit monoclonal anti-ACC Cell Signaling Technology Cat#3676S; RRID: AV_2219397 Rabbit monoclonal anti-FASN Cell Signaling Technology Cat#3180S; RRID: AB_2100796 Rabbit monoclonal anti-SCD1 Cell Signaling Technology Cat#2794S; RRID: AB_2183099 Donkey polyclonal anti-Rabbit IgG Cytiva Cat# NA934-1ML; RRID: AB_772206 Mouse monoclonal anti-EpCAM (G8.8) DSHB Cat#G8.8; RRID: AB_2098655 Bacterial and virus strains pAAV-U6-SA-BbsI-MluI-gRNA-HLPSACas9-HA-OLLAS-spA This Paper vETV_0015 pAAV-U6-SA-mCyp7a1-gRNA6-HLPSACas9-HA-OLLAS-spA This Paper vETV_0028 pAAV-U6-SA-mCyp8b1-gRNA1-HLPSACas9-HA-OLLAS-spA This Paper vETV_0032 pAAV-U6-SA-mCyp2c70-gRNA4-HLPSACas9-HA-OLLAS-spA This Paper vETV_0033 pAAV-U6-SA-mCyp2a12-gRNA6-HLPSACas9-HA-OLLAS-spA This Paper vETV_0057 Biological samples Human Bile Human De-identified Chemicals, peptides, and recombinant proteins Sodium cholate Sigma-Aldrich Cat#C9282; Cas: 206986-87-0 Sodium taurocholate Sigma-Aldrich Cat#T4009; Cas: 345909-26-4 Chenodeoxycholic acid Sigma-Aldrich Cat#C9377; Cas: 474-25-9 Taurochenodeoxycholic acid (sodium salt) Cayman Chemical Cat#20275; Cas: 6009-98-9 Tauro-β-muricholic acid (sodium salt) Cayman Chemical Cat#20289; Cas: 145022-92-0 Sodium deoxycholate Sigma-Aldrich Cat#D6750; Cas: 302-95-4 Taurodeoxycholic acid, sodium salt Millipore Cat#580221; Cas: 1180-95-6 Ursodeoxycholic acid Sigma-Aldrich Cat#U5127; Cas: 128-13-2 Tauroursodeoxycholic acid, sodium salt Millipore Cat#580549; Cas: 35807-85-3 Sodium taurolithocholate Sigma-Aldrich Cat#T7515; Cas: 6042-32-6 Sodium glycocholate Chem-Impex Cat#27530; Cas: 863-57-0 Sodium glycochenodeoxycholate Chem-Impex Cat#21506; Cas: 16564-43-5 Glycodeoxycholic acid, sodium salt Chem-Impex Cat#21779; Cas: 16409-34-0 Glyco-chenodeoxycholic acid Sigma-Aldrich Cat#G0759; Cas: 16564-43-5 Aprotinin Sigma-Aldrich Cat# A6279; Cas: 9087-70-1 Dipeptidyl peptidase 4 (DPP-4) Sigma-Aldrich Cat# D38225MG LipidTOX Red ThermoFisher Cat#H34476 5α cholestane Sigma Aldrich Cat# C8003; Cas: 481-21-0 trinonadecanoin (C17:1) Nu-chek Prep Cat# T-165; Cas: 26536-13-0 cholesterol Sigma Aldrich Cat# C3045; Cas: 57-88-5 (Continued on next page) Cell Metabolism 38, 1–18.e1–e10, January 6, 2026 e1 .. REAGENT or RESOURCE SOURCE IDENTIFIER GLC96 Lipid Standards (mixed lipid standards) Nu-chek Prep Cat# GLC96 GLC96C Lipid Standards (mixed lipid standards) Nu-chek Prep Cat# GLC96C Deuterium oxide Sigma Aldrich Cat# 151882; Cas: 7789-20-0 Sucrose Polybehenate CarboMer Cas: 56449-50-4 coumarin 6 Sigma Aldrich Cat#442631; Cas: 38215-36-0 1,2-dioleoyl-sn-glycero-3-phosphocholine Avanti Polar Lipids Cat#850375; Cas: 4235-95-4 C18:0-d2 Cayman Cat#28150; Cas: 19905-58-9 C18:1-d17 Cayman Cat#9000432; Cas: 223487-44-3 C18:2-d11 Cayman Cat#9002193 GlutaMAX ThermoFisher Scientific Cat#35050061 N2 supplement Fisher Scientific Cat#17502-048 B27 supplement Fisher Scientific Cat#17504404 EGF Peprotech Cat#315-09; Cas: 62253-63-8 A83-01 Med Chem Express Cat#HY-10432; Cas: 909910-43-6 SB202190 Med Chem Express Cat#HY10295; Cas: 152121-03-7 Y-27632 Med Chem Express Cat#HY-10071; Cas: 146986-50-7 CHIR99021 Stem Cell Technologies Cat#72054; Cat: 252917-06-9 IGF-1 Med Chem Express Cat#HY-P70788 FGF2 Med Chem Express Cat#HY-P7004 Gastrin Med Chem Express Cat#HY-P2671 BMP-2 Med Chem Express Cat#HY-P7006 BMP-4 Med Chem Express Cat#HY-P7007 Orlistat TCI America Cat# O0381; Cas: 96829-58-2 Protease inhibitor cocktail tablets Med Chem Express Cat# HY-K0011 Phenylmethanesulfonyl fluoride Sigma Aldrich Cat#93482-50mL-F; Cas: 329-98-6 Calpain Inhibitor Sigma Aldrich Cat# A6185-25 mg; Cas: 110044-82-1 Critical commercial assays U-PLEX Custom Metabolic Group 1 Meso Scale Discovery Cat#K152ACM-1 Teco Diagnostics ALT Liquid Reagent Kinetic Method Kit Teco Diagnostics Cat# A524-150 DNeasy PowerSoil Pro Kit Qiagen Cat#47126 Qubit 1X dsDNA HS Assay Kit Invitrogen Cat#Q33231 Illumina DNA Prep workflow Invitrogen Cat#20060059 KAPA Pure Beads Roche Cat#07983271001 RNeasy mini kit Qiagen Cat#74104 KAPA RNA Hyperprep Kit KAPA Biosystems Cat# KK8541 KAPA Unique Duel-Indexed Adaptor Kit KAPA Biosystems Cat# KK8727 Bicinchoninic acid protein assay Fisher Cat#PI23227 Deposited data Microbiome Sequencing Data NCBI BioProject PRJNA1302405 Bulk Liver RNA Sequencing Data NCBI GEO GSE304800 Source Data This Paper Data S1 Experimental models: Cell lines HEK293T ATCC Cat#CRL-3216 De-identified human jejunal enteroids Dr. Martin Martin, UCLA N/A Experimental models: Organisms/strains Mouse: C57BL/6J The Jackson Laboratory Jax: 000664 (Continued on next page) e2 Cell Metabolism 38, 1–18.e1–e10, January 6, 2026

    Recombinant:

    Article Title: Bile acids regulate lipid metabolism through selective actions on fatty acid absorption.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit polyclonal anti-CYP7A1 Novus Cat#NBP3-04836 lot 5500012145; RRID: AB_2255011 Rabbit polyclonal anti-CYP8B1 Abcam Cat#ab191910; RRID: AB_2828000 Rabbit polyclonal anti- rat CYP2C22 (mouse CYP2C70) Gift from Edward T. Morgan (Emory University) N/A Rabbit monoclonal anti-PDI Cell Signaling Technology Cat#3501S; RRID: AB_2156433 Rabbit monoclonal anti-ACC Cell Signaling Technology Cat#3676S; RRID: AV_2219397 Rabbit monoclonal anti-FASN Cell Signaling Technology Cat#3180S; RRID: AB_2100796 Rabbit monoclonal anti-SCD1 Cell Signaling Technology Cat#2794S; RRID: AB_2183099 Donkey polyclonal anti-Rabbit IgG Cytiva Cat# NA934-1ML; RRID: AB_772206 Mouse monoclonal anti-EpCAM (G8.8) DSHB Cat#G8.8; RRID: AB_2098655 Bacterial and virus strains pAAV-U6-SA-BbsI-MluI-gRNA-HLPSACas9-HA-OLLAS-spA This Paper vETV_0015 pAAV-U6-SA-mCyp7a1-gRNA6-HLPSACas9-HA-OLLAS-spA This Paper vETV_0028 pAAV-U6-SA-mCyp8b1-gRNA1-HLPSACas9-HA-OLLAS-spA This Paper vETV_0032 pAAV-U6-SA-mCyp2c70-gRNA4-HLPSACas9-HA-OLLAS-spA This Paper vETV_0033 pAAV-U6-SA-mCyp2a12-gRNA6-HLPSACas9-HA-OLLAS-spA This Paper vETV_0057 Biological samples Human Bile Human De-identified Chemicals, peptides, and recombinant proteins Sodium cholate Sigma-Aldrich Cat#C9282; Cas: 206986-87-0 Sodium taurocholate Sigma-Aldrich Cat#T4009; Cas: 345909-26-4 Chenodeoxycholic acid Sigma-Aldrich Cat#C9377; Cas: 474-25-9 Taurochenodeoxycholic acid (sodium salt) Cayman Chemical Cat#20275; Cas: 6009-98-9 Tauro-β-muricholic acid (sodium salt) Cayman Chemical Cat#20289; Cas: 145022-92-0 Sodium deoxycholate Sigma-Aldrich Cat#D6750; Cas: 302-95-4 Taurodeoxycholic acid, sodium salt Millipore Cat#580221; Cas: 1180-95-6 Ursodeoxycholic acid Sigma-Aldrich Cat#U5127; Cas: 128-13-2 Tauroursodeoxycholic acid, sodium salt Millipore Cat#580549; Cas: 35807-85-3 Sodium taurolithocholate Sigma-Aldrich Cat#T7515; Cas: 6042-32-6 Sodium glycocholate Chem-Impex Cat#27530; Cas: 863-57-0 Sodium glycochenodeoxycholate Chem-Impex Cat#21506; Cas: 16564-43-5 Glycodeoxycholic acid, sodium salt Chem-Impex Cat#21779; Cas: 16409-34-0 Glyco-chenodeoxycholic acid Sigma-Aldrich Cat#G0759; Cas: 16564-43-5 Aprotinin Sigma-Aldrich Cat# A6279; Cas: 9087-70-1 Dipeptidyl peptidase 4 (DPP-4) Sigma-Aldrich Cat# D38225MG LipidTOX Red ThermoFisher Cat#H34476 5α cholestane Sigma Aldrich Cat# C8003; Cas: 481-21-0 trinonadecanoin (C17:1) Nu-chek Prep Cat# T-165; Cas: 26536-13-0 cholesterol Sigma Aldrich Cat# C3045; Cas: 57-88-5 (Continued on next page) Cell Metabolism 38, 1–18.e1–e10, January 6, 2026 e1 .. REAGENT or RESOURCE SOURCE IDENTIFIER GLC96 Lipid Standards (mixed lipid standards) Nu-chek Prep Cat# GLC96 GLC96C Lipid Standards (mixed lipid standards) Nu-chek Prep Cat# GLC96C Deuterium oxide Sigma Aldrich Cat# 151882; Cas: 7789-20-0 Sucrose Polybehenate CarboMer Cas: 56449-50-4 coumarin 6 Sigma Aldrich Cat#442631; Cas: 38215-36-0 1,2-dioleoyl-sn-glycero-3-phosphocholine Avanti Polar Lipids Cat#850375; Cas: 4235-95-4 C18:0-d2 Cayman Cat#28150; Cas: 19905-58-9 C18:1-d17 Cayman Cat#9000432; Cas: 223487-44-3 C18:2-d11 Cayman Cat#9002193 GlutaMAX ThermoFisher Scientific Cat#35050061 N2 supplement Fisher Scientific Cat#17502-048 B27 supplement Fisher Scientific Cat#17504404 EGF Peprotech Cat#315-09; Cas: 62253-63-8 A83-01 Med Chem Express Cat#HY-10432; Cas: 909910-43-6 SB202190 Med Chem Express Cat#HY10295; Cas: 152121-03-7 Y-27632 Med Chem Express Cat#HY-10071; Cas: 146986-50-7 CHIR99021 Stem Cell Technologies Cat#72054; Cat: 252917-06-9 IGF-1 Med Chem Express Cat#HY-P70788 FGF2 Med Chem Express Cat#HY-P7004 Gastrin Med Chem Express Cat#HY-P2671 BMP-2 Med Chem Express Cat#HY-P7006 BMP-4 Med Chem Express Cat#HY-P7007 Orlistat TCI America Cat# O0381; Cas: 96829-58-2 Protease inhibitor cocktail tablets Med Chem Express Cat# HY-K0011 Phenylmethanesulfonyl fluoride Sigma Aldrich Cat#93482-50mL-F; Cas: 329-98-6 Calpain Inhibitor Sigma Aldrich Cat# A6185-25 mg; Cas: 110044-82-1 Critical commercial assays U-PLEX Custom Metabolic Group 1 Meso Scale Discovery Cat#K152ACM-1 Teco Diagnostics ALT Liquid Reagent Kinetic Method Kit Teco Diagnostics Cat# A524-150 DNeasy PowerSoil Pro Kit Qiagen Cat#47126 Qubit 1X dsDNA HS Assay Kit Invitrogen Cat#Q33231 Illumina DNA Prep workflow Invitrogen Cat#20060059 KAPA Pure Beads Roche Cat#07983271001 RNeasy mini kit Qiagen Cat#74104 KAPA RNA Hyperprep Kit KAPA Biosystems Cat# KK8541 KAPA Unique Duel-Indexed Adaptor Kit KAPA Biosystems Cat# KK8727 Bicinchoninic acid protein assay Fisher Cat#PI23227 Deposited data Microbiome Sequencing Data NCBI BioProject PRJNA1302405 Bulk Liver RNA Sequencing Data NCBI GEO GSE304800 Source Data This Paper Data S1 Experimental models: Cell lines HEK293T ATCC Cat#CRL-3216 De-identified human jejunal enteroids Dr. Martin Martin, UCLA N/A Experimental models: Organisms/strains Mouse: C57BL/6J The Jackson Laboratory Jax: 000664 (Continued on next page) e2 Cell Metabolism 38, 1–18.e1–e10, January 6, 2026



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    95
    Chem Impex International bile salt hydrolysis bsh activity
    OxLDL increases ASMase expression and promotes sphingomyelin (SM) catabolism. A , schematic illustration of SM catabolism. SM is hydrolyzed by ASMase to generate ceramide and phosphatidylcholine. Ceramidases convert ceramides into sphingosine and fatty acids. B , Western blot detection of ASMase expression is performed in cells treated with varying concentrations of oxLDL (50–120 μg/ml; one-way ANOVA followed by Tukey’s post hoc test, n = 3). C , RT-qPCR analysis measures ASMase mRNA levels in oxLDL (50 μg/ml) treated macrophages. D , ASMase enzymatic activity is assessed in cells treated with oxLDL at concentration of 50 μg/ml. E , OxLDL-treated cells are seeded on coverslip and incubated with SM-binding <t>protein,</t> <t>lysenin-His</t> (1 μg/ml). Membrane SM is detected using immunofluorescence staining and quantified by flow cytometry. F – H , total cellular levels of SM and ceramides, and SM/ceramide ratio are measured by LC-MS/MS in oxLDL-treated cells (50 μg/ml). I and J , lipidomics analysis of specific SM and ceramide species in cells treated with oxLDL (50 μg/ml). All comparisons were conducted with Student's t test except in ( B ) (mean ± SD, n = 3). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001. ns, not significant.
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    OxLDL increases ASMase expression and promotes sphingomyelin (SM) catabolism. A , schematic illustration of SM catabolism. SM is hydrolyzed by ASMase to generate ceramide and phosphatidylcholine. Ceramidases convert ceramides into sphingosine and fatty acids. B , Western blot detection of ASMase expression is performed in cells treated with varying concentrations of oxLDL (50–120 μg/ml; one-way ANOVA followed by Tukey’s post hoc test, n = 3). C , RT-qPCR analysis measures ASMase mRNA levels in oxLDL (50 μg/ml) treated macrophages. D , ASMase enzymatic activity is assessed in cells treated with oxLDL at concentration of 50 μg/ml. E , OxLDL-treated cells are seeded on coverslip and incubated with SM-binding protein, lysenin-His (1 μg/ml). Membrane SM is detected using immunofluorescence staining and quantified by flow cytometry. F – H , total cellular levels of SM and ceramides, and SM/ceramide ratio are measured by LC-MS/MS in oxLDL-treated cells (50 μg/ml). I and J , lipidomics analysis of specific SM and ceramide species in cells treated with oxLDL (50 μg/ml). All comparisons were conducted with Student's t test except in ( B ) (mean ± SD, n = 3). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001. ns, not significant.

    Journal: The Journal of Biological Chemistry

    Article Title: Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake

    doi: 10.1016/j.jbc.2025.110213

    Figure Lengend Snippet: OxLDL increases ASMase expression and promotes sphingomyelin (SM) catabolism. A , schematic illustration of SM catabolism. SM is hydrolyzed by ASMase to generate ceramide and phosphatidylcholine. Ceramidases convert ceramides into sphingosine and fatty acids. B , Western blot detection of ASMase expression is performed in cells treated with varying concentrations of oxLDL (50–120 μg/ml; one-way ANOVA followed by Tukey’s post hoc test, n = 3). C , RT-qPCR analysis measures ASMase mRNA levels in oxLDL (50 μg/ml) treated macrophages. D , ASMase enzymatic activity is assessed in cells treated with oxLDL at concentration of 50 μg/ml. E , OxLDL-treated cells are seeded on coverslip and incubated with SM-binding protein, lysenin-His (1 μg/ml). Membrane SM is detected using immunofluorescence staining and quantified by flow cytometry. F – H , total cellular levels of SM and ceramides, and SM/ceramide ratio are measured by LC-MS/MS in oxLDL-treated cells (50 μg/ml). I and J , lipidomics analysis of specific SM and ceramide species in cells treated with oxLDL (50 μg/ml). All comparisons were conducted with Student's t test except in ( B ) (mean ± SD, n = 3). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001. ns, not significant.

    Article Snippet: After blocking with 2% BSA/PBS, 1 μg/ml lysenin-His (TargetMol) dissolved in the blocking solution was added and incubated at 4 °C overnight.

    Techniques: Expressing, Western Blot, Quantitative RT-PCR, Activity Assay, Concentration Assay, Incubation, Binding Assay, Membrane, Immunofluorescence, Staining, Flow Cytometry, Liquid Chromatography with Mass Spectroscopy